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Diabetic Retinopathy

Diabetic retinopathy is the most common eye affliction resulting from diabetes. In the worst cases, it can result in complete vision loss. Both diabetes 1 and 2 can lead to diabetic retinopathy, which affects almost 50% of diabetics. In the United States, diabetic retinopathy is the leading cause of blindness. Early detection and treatment are critical to minimize the risk of profound vision loss in diabetics, and with proper treatment, the risk of complete vision loss is low.

What is Diabetic Retinopathy?

Diabetic retinopathy is caused by high blood sugar levels. High blood sugar affects many parts of the body, including the capillaries that bring nourishment to the retina. The retina is responsible for transferring visual images to the brain.

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Diabetic retinopathy occurs in two forms, and usually affects both eyes.

1) Nonproliferative diabetic retinopathy (NPDR)

Also referred to as background diabetic retinopathy, this is the most common and early stage of this eye disease. Symptoms are often minimal, and even nonexistent. In nonproliferative diabetic retinopathy, very small bulges form in the weakened capillaries of the retina. These bulges, called microaneurysms, can leak fluid and blood into the retina. As well, bunches of swollen nerve fibers can appear. The end result can be either swelling of the macula, the central part of the retina, or a reduction of blood flow to the macula. This interference with the proper functioning of the macula can result in a loss of central vision.

2) Proliferative diabetic retinopathy (PDR)

PDR is an advanced form of diabetic retinopathy and is diagnosed when abnormal growth of blood vessels in the optic nerve or retina is present. The growth of these blood vessels results from the actual closing of capillaries in the retina and can result in decreased central and peripheral vision. The closing of capillaries results from high blood sugar levels in the body, and can result in several complications, including leaking blood vessels, retinal detachment, and the development of neovascular glaucoma.

Many diabetics commonly experience blurred vision. Rapid changes in blood sugar levels can lead to the accumulation of blood sugar byproducts in the lens. This causes the lens to swell and makes distant objects appear blurred or fuzzy (nearsightedness). Macular swelling can also occur and cause the capillaries to hemorrhage. This causes spots to appear in the visual field.

Are you at risk?

Both type 1 and type 2 diabetes puts a patient at risk for diabetic retinopathy. The risk increases the longer a patient has diabetes. Diabetics can minimize their risks by ensuring that blood sugar levels are properly controlled, by controlling high blood pressure and blood cholesterol, and by controlling body weight. Pregnancy and kidney disease also put a patient at increased risk.

Diagnosing Diabetic Retinopathy

Diabetics should undergo a comprehensive eye exam at least once a year. A doctor will look for any of the following signs of diabetic retinopathy.

- Swelling of the retina
- Hemorrhage in the retina
- Leaking capillaries
- Retinal fatty deposits
- Closure in capillaries
- Optic nerve damage
- Formation of new blood vessels
- Vitreous hemorrhage
- Microaneurysms
- Formation of scar tissue/retinal detachment

If you doctor suspects that you have leaking blood vessels in the eye, he or she may perform a test called fluorescein angiography. In this test, a dye is injected into a vein in the arm, a blue light is used to observe the eyes as the dye circulates. If the blood vessels are leaking, they will appear bright yellow as the circulates.

Diabetic retinopathy can be successfully treated in most diabetics. Although it cannot be cured, it can be kept under control such that complete vision loss and reduced vision loss is kept to a minimum.


Resources: Find comprehensive coverage of diabetic retinopathy from the National Eye Institute. The Mayo Clinic offers images and explanations of how diabetic retinopathy affects the retina.

 

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